We are a private, non-profit initiative with the mission to enable people to vastly extend their healthy lifespan and be part of the first generation to cure aging.
The world has started the transition from an era where we were utterly helpless about our aging process to one where aging is under full medical control, and age-related diseases are a thing of the dark past.
We are not there yet, but the theoretical groundwork has been laid out, and scientists have successfully started working on the fundamentals. The first human rejuvenation therapies are under development, some of them are even available today.
For people close to the actual science, rejuvenation is not a matter of 'if' anymore but rather 'when' and whether it will be soon enough for 'us'.
Senolytics, NAD+, Lipid Replacement, Decalcification, mTOR Inhibitors, Geroprotectors, ... - the first generation of human rejuvenation therapies is available today.
However, the field is still very young and information often spotty. New therapies are emerging, and existing ones are updated or replaced. A real challenge for those of us who want to take advantage of this exciting development as soon as possible.
To overcome this, we have set out to continuously identify new therapies and systematically evaluate them on risks, benefits, procedures and potential application.
In addition to the first generation of rejuvenation therapies, there is already a vast amount of cutting-edge medical knowledge that can be used right now to maximize our health and extend our healthy lifespan.
Unfortunately, most of it remains unused because it is spread out over various experts, specialized communities, blogs, books, and websites, or deeply buried in scientific research, making informed decisions regarding one's personal health quite hard.
We decided to change this by using the principles of evidence-based medicine to create a holistic and actionable guide on what can be done at present to maximize our health and well-being.
Among all the long-term strategies to undo or prevent our aging process, the engineering approach to repair the damage caused by aging on a cellular and molecular level is by far the most promising. Particularly regarding dramatic, actionable results in the mid-term future.
However, this young field of research still lacks the attention that it deserves. We think it is essential to accelerate the development of these exciting technologies as much as possible. Thus we fund some of the most promising research in this area.
To accelerate the development of human rejuvenation therapies, we have teamed up with the SENS Research Foundation and created the annual Undoing Aging Conference in Berlin.
Undoing Aging is focused on molecular and cellular repair of age-related damage. It brings together scientists and startups from around the globe, who are leading the charge in maintaining and restoring full health in old age. Topics include stem cells, senescent cells, immunotherapies, biomarkers, and drug discovery.
To accelerate the translation of basic research on molecular and cellular repair of age-related damage into actual human therapies we directly support the creation of startups in this young industry.
The teams develop therapies in the area of Senolytics, Lysosomal Clearance, Induced Tissue Regeneration, Stemcell Restoration, Young Plasma Factors, AGE Breakers, Novel Cancer Therapies, and Aging Biomarkers.
Taking advantage of leading-edge rejuvenation therapies and driving the transition to a world where it is possible to vastly extend our healthy life spans is a huge endeavor. A community sharing the same vision, all collaborating and supporting each other is really helpful in this regard.